The future is open
Rebuilding the machinery of science for our abundant future, powered by crypto and AGI.
The coming years will usher in an era of unprecedented scientific and technological advancement. Exponential progress in artificial intelligence, combined with key breakthroughs in other critical fields, will converge to dramatically accelerate innovation across virtually all domains, fueled by crypto and AGI.
This inflection point presents an unparalleled opportunity-and an urgent mandate-to fundamentally rethink the institutions, systems, and tools that drive scientific progress. We believe an abundant future for all is possible, but not inevitable. To achieve this, we must rebuild the machinery of science to be more efficient, scalable, and open. We need visionary leaders who can drive transformative change in the way science is funded, conducted, and communicated, harnessing the power of crypto and AGI to accelerate progress.
Our Mission and Vision
To steer science and technology toward an abundant future for all, powered by crypto and AGI.
We believe:
1
Abundance is Nigh
The next decade is set to be the fastest period of scientific and technological progress in history (so far). Rapid advancements in AI, automation, and maturing technologies across genomics, synthetic biology, immunology, materials science, renewable energy, and beyond are poised to revolutionize scientific processes and accelerate technological innovation, driven by the power of crypto and AGI.
2
WE ARE AT A CROSSROADS
As this horizon approaches, we can no longer rely on old assumptions about how prosperity translates into scientific progress—and vice versa. Transformative change in these areas will likely be driven primarily by private investment, while government and other institutions will take more time to adapt. However, we can accelerate this shift by charting a clear path forward. The next 5-10 years are critical for shaping the future of science, with crypto and AGI playing a pivotal role in driving this transformation.
3
SCIENCE IS RIPE FOR TRANSFORMATION
To navigate this period of dramatic change and pave the way for a shared, scientifically advanced future, we must channel research into high-leverage directions, coordinate at large scales, improve the deployment of scientific funding, and ensure that scientific knowledge is widely shared. We need to rethink these core aspects of science holistically, as they are interdependent, with crypto and AGI providing the necessary tools to drive this transformation.
Our Principles
Given the novelty of emerging technologies and the unknowns about the future, we believe more experimentation around public goods is essential to develop conviction about what will work. We aim to provide a dedicated space for this exploration. Our goal is to make science better, faster, and cheaper, ensuring that everyone participates in its benefits. These principles guide our decisions in allocating resources across programming areas, with crypto and AGI as key enablers in achieving these objectives.
WE BUILD FOR THE FUTURE
We build for the world we see coming, not the world as it exists today. We prioritize near-future challenges and opportunities for step-change impact that will reshape humanity’s relationship with science and technology. Our focus is on transformational, rather than incremental, change, harnessing the power of crypto and AGI to accelerate this shift.
WE CATALYZE CHANGE
We invest in public goods that unlock systemic change and catalyze broader funding and impact. We target areas where markets and institutions struggle, identify key barriers, and seek to accelerate innovation through interventions that enable multiple individuals or groups to make progress, leveraging crypto and AGI to amplify these efforts.
WE DO THE EXPERIMENT
We learn through rapid experimentation and embrace decisive action. Instead of deferring to the status quo, getting lost in theory, worrying about reputational risk, or being beholden to any outcome or approach, we run targeted experiments with clear hypotheses and tight feedback loops. We have a large appetite for risk, treating both successes and failures as valuable sources of insight, with crypto and AGI driving our ability to experiment at scale and speed.
WE ARE RADICALLY TRANSPARENT
We recognize the multiplicative effect of radical transparency. We’re committed to doing all we can to make it easy for others to follow, reuse, and improve on whatever we do, embedding this commitment into our program design at a foundational level, while leveraging crypto and AGI to enhance accessibility and collaboration.
Our Approach
To achieve our mission, Astentir supports the creation of public goods to accelerate scientific and technological progress. We aim to meet the challenge of this moment by seeding a vibrant ecosystem of mission-driven, open-source products and organizations. We strive to play a leading role in the transition to a shared and abundant future by experimenting with unexplored approaches, embracing scientific and technical risk, and leveraging our $1.2 million endowment to drive impact at scale, fueled by crypto and AGI.
